I like my party: Alyss, Brendan, Andras and me as an elemental mage (fire, ice and lightning).
First Round: Sub Zero (me), Powder Bomb (Alyss), Burning Weapons (Brendan), Encourage (Andras)
Result: enemies don't make damage for 5 rounds and my damage gets boostes.
Second Round: Inferno (me), Concentration (Alyss), Magical Weapons (Brendan), Smash Armor against the strongest opponent (Andras)
From the third round on I can rain damage, mostly via AoE.
Works perfectly against foes who mostly deal damage, but even against debuffers...