Hmmm, also, there always seems to be that final question: which class is the best?
I've done both Psycho and Hydro legend runs as well. I did a psycho shadow build and I have to say it wasn't very good. I had to waste a lot of my turns free-willing or terrifying just to make sure I don't lose health every turn. I would say that psycho shocker is better, but I still think that Psycho is the worst class out of the three, due to its mediocreness in the first zones and its toughness in the last zones.
Hydro I would put at the I would put there at the second-best class, just behind Bio. It is really amazing in the first zones, nevertheless, once you get to Zones 6 and 7, Cold Hydro is way worse than Psycho or Bio, due to damage output. Hot hydro is not even worth it either, with no defense or tactical abilities available to use.
The reasons that I think Bio is the best class is:
A, Speed Bio Dominates Zones 6 and 7
B, It has Crystallize as a great tactical move, and unlike shock coma for Psycho, you can Crystallize someone regardless of health left.
C, It is over-average in the first Zones, which makes it ultimately beat out Hytdro, though I do admit that Hydro is stronger in that category
D, There are a lot better Strength items than Instinct items giving you higher damage with items like Emerald Death, Annihilation, and the Unholy Runeblade. The best Instinct weapons are worse in stats, and are Shandor's Darkstaff, Poseidon's Fury, and Law Binder, which you can't really use until level 21 anyway. There's also WOTC but you can't even use it until zone 6, where there are weapons almost equal or even better than that.