Yes, I'm pretty sure that using Dark Infusion on Yosuke would still make him take damage. Really all you need I'm pretty sure is an insecurity, epiphany, and an implosion, but remember to keep him stunned so he can't use his fire attack.
Because for Biological you can just get him down quick and easily using the Withdrawal combo. For Psycho, you could use the Shock Coma combo, if you have the abilities (Explained at the bottom of my guide)