I got the Wacom Intous4 (right before they released 5) I'd say save some money and get a 4. it's really good, the pressure sensor is amazing, and you get different nubs for your pen, to change the feel.
also, it works great with: PhotoshopCS5/CS6 and autodesk sketchbook pro, it comes bundled with express, but I got pro from autodesk since I am a student.