wait lord saddler? hes only from RE4 the best villian is.... Albert wesker from all resident evil games! hes basicly the creator of the t-virus and he can control himself! and his voice is creepy but cool.
people just copy the same villin every time becuase they see that someone else put that up and they dont know any becuase they are 4 year old b low jobs
lol, I'm gonna go with Donkey Kong, from the original Donkey Kong game (not country). I mean he throws barrels at u. whats more evil than that? plus hes Mario's 1st nemesis.
between bowser, ganon, and the most evil villain in a game I think would be Jack of Blades from Fable jsut because he'll kill anyone he sees pretty much, and he totally screws up the world and ya...that kind of stuff, probably could think of a lot of villains more evil than him, but I don't want to think right now