Darkroot the endless different creatures you can create can act differently and even play differently so that would make the game different, personally I think there is lots of replay value. I cant wait for it to come out.
Billions of ways to create creature and dominate the universe it look only like a game that's interesting only one time through. Plus I know more about this game than like anyone I knew it was going to be made like 5 years ago. I also bought and used the creature creator.
They don't really act differently they act differently and you don't really play differently since at the end your still going to have a spacecraft to destroy the universe with.