Probably flcl... Fooly Cooly... It's a Japanese show. It's only 6 episodes, but it's confusing as hell... That's why I like it. It's one of those shows that you don't understand it until the end.
Um Family guy has gotten pretty boring because I have seen every show. I do like South Park because they make new ones every so often.
I HATE ATHF, and Robot Chicken though. It's just utter stupidity >.>
All time favourite is the X Files...love Gillian Anderson. The stories were on the whole great - altho they did have a few terrible eps. It was a show that scared a whole generation and had us all ask if we were alone in the universe.
I know people will say it was all done before - Star Trek and the Twilight Zone having covered most of the stuff before - but it still had it's own scope on things. Sometimes beautiful (Momento Mori) sometimes weird (Home) and sometimes just down right scary (Toombs), I don't think it'll be beaten.