So I was sort of mistaken about the 4-skill build. It won't be able to beat bios with around 8000 HP or more if they have Integrity maxed. However, it can still beat a psycho or hydro of any HP (even hacked) as long as it goes first. Plus, there are still 16 unspent skill points that I'm not using but which I could use to improve the damage.
Anyway, the build:
START_!&!%,*$*,2,0.859259999999978,3,15,undefined,HIGH,true,false,true,JOOB,5,2,23521,0,30,16,0,0,257,35,115,463,122,*$*,EMPTY,10,13,9,10,14,0,0,0,0,0,0,0,0,*^*,25,88,78,55,*^*,25,88,78,55,*^*,25,88,78,55,*^*,25,88,78,55,*^*,25,88,78,55,*^*,25,88,78,55,*^*,2,2,2,2,2,2,*^*,149,172,0,0,0,0,0,172,*^*,1,6,172,149,142,138,133,*^*,NODATA,*^*,0,4,0,1,0,0,0,1,0,0,0,1,0,0,4,0,0,0,0,0,0,0,1,0,0,3,0,3,0,0,0,0,0,0,0,0,0,0,*^*,0,0,0,133,0,0,0,138,0,0,0,142,0,0,149,0,0,0,0,0,0,0,0,0,0,0,0,172,0,0,0,0,0,0,0,0,0,0,*^*,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,*^*,0,INTEGRITY4,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,MARATHON1,0,0,EVOLUTION3,0,0,0,0,0,0,0,0,0,0,0,0,*^*,655,649,603,564,658,567,504,527,0,0,0,0,637,638,609,610,611,651,0,0,575,630,0,652,0,613,0,615,616,0,0,0,639,640,0,0,0,*^*,0,1,2,3,-1,-1,*^*,30,30,30,23,12,12,*^*,627,628,570,620,631,658,0,*^*,642,623,644,645,626,649,0,*^*,637,638,609,610,641,658,0,*^*,607,608,639,640,641,658,0,*^*,0,0,0,0,0,0,0,*^*,0,0,0,0,0,0,0,*^*,116,0,0,0,0,0,0,0,*^*,0,0,0,0,0,0,0,0,*^*,0,0,0,0,0,0,0,0,*^*,0,0,0,0,0,0,0,0,*^*,0,0,0,0,0,0,0,0,*^*,0,0,0,0,0,0,0,0,*^*,0,0,0,0,0,0,0,0,*^*,0,0,0,121,49,0,0,0,*^*,0,0,0,0,78,0,0,0,*^*,0,0,0,0,69,0,0,0,*^*,0,0,0,0,0,0,0,0,*^*,0,0,0,0,0,0,0,0,*^*,0,0,0,0,0,*^*,88,189,15,390,15,*^*,94,109,334,136,0,*^*,211,303,0,126,0,*^*,198,320,0,88,0,*^*,0,0,0,0,0,*^*,0,0,*^*,91.902044137296,91.3944606033273,97.5547535576103,7.18193637017697,0,0,*^*,1,4,32,71,2,4,*$*,14,6.01481999999985,21,105,undefined,HIGH,true,false,true,JOOB,35,14,164647,0,210,112,0,0,1799,245,805,3241,854,*$*,EMPTY,70,91,63,70,98,0,0,0,0,0,0,0,0,*^*,175,616,546,385,*^*,175,616,546,385,*^*,175,616,546,385,*^*,175,616,546,385,*^*,175,616,546,385,*^*,175,616,546,385,*^*,14,14,14,14,14,14,*^*,1043,1204,0,0,0,0,0,1204,*^*,7,42,1204,1043,994,966,931,*^*,NODATA,*^*,0,28,0,7,0,0,0,7,0,0,0,7,0,0,28,0,0,0,0,0,0,0,7,0,0,21,0,21,0,0,0,0,0,0,0,0,0,0,*^*,0,0,0,931,0,0,0,966,0,0,0,994,0,0,1043,0,0,0,0,0,0,0,0,0,0,0,0,1204,0,0,0,0,0,0,0,0,0,0,*^*,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,*^*,0,INTEGRITY4,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,MARATHON1,0,0,EVOLUTION3,0,0,0,0,0,0,0,0,0,0,0,0,*^*,4585,4543,4221,3948,4606,3969,3528,3689,0,0,0,0,4459,4466,4263,4270,4277,4557,0,0,4025,4410,0,4564,0,4291,0,4305,4312,0,0,0,4473,4480,0,0,0,*^*,0,7,14,21,-7,-7,*^*,210,210,210,161,84,84,*^*,4389,4396,3990,4340,4417,4606,0,*^*,4494,4361,4508,4515,4382,4543,0,*^*,4459,4466,4263,4270,4487,4606,0,*^*,4249,4256,4473,4480,4487,4606,0,*^*,0,0,0,0,0,0,0,*^*,0,0,0,0,0,0,0,*^*,812,0,0,0,0,0,0,0,*^*,0,0,0,0,0,0,0,0,*^*,0,0,0,0,0,0,0,0,*^*,0,0,0,0,0,0,0,0,*^*,0,0,0,0,0,0,0,0,*^*,0,0,0,0,0,0,0,0,*^*,0,0,0,0,0,0,0,0,*^*,0,0,0,847,343,0,0,0,*^*,0,0,0,0,546,0,0,0,*^*,0,0,0,0,483,0,0,0,*^*,0,0,0,0,0,0,0,0,*^*,0,0,0,0,0,0,0,0,*^*,0,0,0,0,0,*^*,616,1323,105,2730,105,*^*,658,763,2338,952,0,*^*,1477,2121,0,882,0,*^*,1386,2240,0,616,0,*^*,0,0,0,0,0,*^*,0,0,*^*,643.314308961072,639.761224223291,682.883274903272,50.2735545912388,0,0,*^*,7,28,224,497,14,28,*$*,7,*$*,!&!%_END
If it doesn't go first, you've either hacked or are using a max speed bio. Assuming it does go first, just repeat this simple pattern:
Crystallize->Pass->Pass->Infect
You'll never run out of focus and the enemy will never get to do anything. It's boring as hell but it will kill anything that doesn't regenerate more than 240 or so HP a turn passively (through Integrity). It's mostly just funny to kill stuff with only 3 skills on the bar and only 4 actually affecting anything.