1. The beginning will be hard because you do not have very good genomes yet. Keep trying and don't get frustrated, when you get to the good genomes everything will be good. 2. The best trait to invest in is Reproduction. Quantity will always trump quality. 3. After, go for Strength and Defense. Defense will help you survive (something you lack greatly in the beginning) and strength will help you capture cells more easily. 4. Agility is worth nothing; it only measures how fast your viruses turn. Speed is nominally useful, but still inferior to fast reproduction. 5. Cancerous cells are the best special cells, followed by bacteria, then red blood, then white blood. Of course, by now you should be making orders in split seconds so as to get them all at approximately the same time. 6. The AI is ruthless, but their main weakness is overpressing the attack, meaning to say that they keep attacking to the point where their defenses are extremely weak. Attack them as soon as this happens. 7. The beginning is the most important stage of the game; it's very hard to get back up if you don't get a lead. You usually start with 100 viruses in one cell, so it's generally best to deploy into two different cells in the first few seconds of the game. 8. The best defense is a good offense. If you can subdue your enemy's cells before they can attack, they will be unable to score major victories. 9. You can't have negative traits (negative speed, agility, etc.), so if you don't have anything there, then don't worry about it. The key to winning is specialization; a well-rounded virus will not do well. 10. Don't be afraid to press X and terminate the experiment. It happens.
My total stats were: 0 Speed, 10 Strength, 0 Agility, 11 Defense (max), 11 Reproduction (max). Although my viruses were very slow, the sheer number of them I could produce in a short time combined with their powerful strength allowed me to steamroller through the opposing viruses. The defense helped protect the cells I had already captured, preventing them from falling back into enemy hands.
This game is a piece of cake, but still insanely fun nonetheless. My favorite build focuses on Speed, Strength and Reproduction. Pretty much capture every special cell and end them. Even comparable numbers in white blood cells don't stand a chance, and if you get ahold of cancer cells.... That's grounds for forfeit right there. Too bad the AI doesn't forfeit =P.