At lvl 25, I've been hitting the mayor for about 14k with poison form, shdw bld, ag expo, and slash. Also use pred form, senses, ag exp, and destroy for alternate nuke. Phys. Dmg, regen, and stat boost talents maxed.
Eddy, i know how you can almost double that, instead of using sharp senses use agile exposure after using shadow blend. 1 of the buffs is that you hit double next turn.