Well, I just got fallout 3, and in a long chain of events, and a few accidents...
I kill Mr. Burke.
So, I was wondering, is it possible to still complete the quest disarming the bomb? I havnt started the quest, but could I disarm the bomb and get the megaton house, achievement, etc?
In the Japanese version of Fallout 3, Mr. Burke does not appear and the player cannot get the Fusion Pulse Charge. The only options are to disarm the nuke or ignore it.
-fallout3 wiki
Some I'm guessing that when Burke isn't there you can't detonate the bomb and kill everyone.
But you can disarm it and people will instantly love you and give you worthless stuff.
If you have any questions about fallout 3 just go to the wiki.