Well a pick up line is a sentence or a phrase generally used by mates to quickly gain the attenion of females and are used to skip hours of meaningless conversation and alert the female that they wish to enguage in sexual activities. Most pick up lines don't work but there still funny to say.
You: "Did you know I'm a palm reader?" Them: "No, go away." or "No, can you read my palm?" You: "Well I am, can I read your palm?" or if they say the second, "Of course!" Them: "No. Bye." They leave. Or, you study their palm intently, running your finger along their lines. Nod knowingly.
You: "Ahh, that's very interesting. It says... made in Heaven."