Endurance in F1 looming, no traits, was finished. Obviously, there is no longer any permafrost.
To do this, a grade 71 ybr (psorek's method for 16c upgraded) gem with 8 amplified g68 16c upgraded gems was used to remove the opposition (set to least hp). This gem did e45 max damage, which is 4e23 damage * 3e21 critical damage. This is enough to kill a monster with 1e49 hp in 10000 (good) shots which takes ~10 minutes game time. This time can be shortened with blade shrines and wake of eternity.
The gem cost 1e29 mana, the full amplifier set cost 1e30 mana, taking about 8 hours to farm.
Also, a tower with an obur grade 90 gem (straight upgraded) was set to random. This slowed monsters to 90% of speed constantly and provided enough mana to keep from dying to banishments, but not enough to upgrade anything.
Used a bp grade 89 gem and a grade 89 bc gem (straight upgraded) set to random to remove most armour and hit point regeneration as well.
Until wave 200, had an obr gem 16c upgraded to grade 69 with 6 grade 68 pure orange 16c upgraded amplifier gems, and three more obr gem traps near that mess.
each gem gained ~1e22 mana per hit, paying off the next upgrade painfully slowly, as these gems cost ~1e29 or 1 million times as much.
Made third wave, before endurance, have e42 hp. This got me to grade 55 16c upgraded gems before endurance for yellows and oranges and amplifiers.
Then enraged each wave in endurance to e37 until wave 200. Sometimes I used gem bombs which spawn "gem wasps" which slow down monsters further.
Next, threw the mana farm into a mana shard when I had enough to take out an e50 wave (which I had calculated beforehand as the max hp to deal with), made my final towers, and fast forwarded until wave 900.
Used shrines for infection, time, blade and , fully upgraded freeze and woe to kill the toughest enemies, which was an e51 spire. When e53 spectres came on the screen, I simply hid my exposed gems and gave it a low grade gem to steal.
Wave 999 had e50 possessed giants x3 which were banished about 5 times before going down. (each banishment in endurance costs 20% of mana pool, so I used a buffer of ~e25 mana to absorb this anticipated hit).
Total time ~9 hours.
I am wizard level ~3000 (One can get to wave 500 and gain billions of xp on any map in about 30 minutes, without using the laborious 16c combination method.). I put ~110 points into pure/dual/triple/quad gem enhancement, ~90 points into orange
and ~90 points into black and have +14 to all skills.
Notes:
http://pl.vc/4c4y6
The main thing limiting mana gain is the max hits per second. Although the level 70 gems say they have ~200,000 hits per second, this is limited to about 40 hits per second for both traps and towers. This reduced mana gain to ~1e24 per second from a theoretical ~1e28 per second. That would pay off the orange grade 70 gems in seconds, not hours.
If the hits per second were increased to the same it says on the screen, grade 150 gems could be made in minutes, not decades, of game time, with the "u" upgrades, but this is not how the game works.
Also, the mana gain from killing or banishing monsters does not scale like the other numbers (although banishment costs 20% of mana pool in endurance).
Alternatively, a shrine of blades and a "juggling" technique could kill the toughest monsters, but the # of demolitions is strictly limited.
The above technique would NOT work for e70 monsters. A grade 73 or grade 76 gem would cost 16 or 256 times as much, do maybe e49 damage tops, and the mana gain would take longer than the time it would take for 999 waves to come and go.
Mana shard mana gain of bomb gems is strictly limited to 5% increase. Even if you had 80 mana shards, this would only give you ~16 times the initial mana, which would get you an upgrade of about 100x the damage at most (1e2, not enough to make a big difference).
This is truly a game where only exponential changes make a difference.