That is a fantastic solo. The first, softer-ish solo before the Darkness Riff is also pwnage.
either More than a Feeling
Really? I think that solo is decent, but not fantastic...
or Comfortably Numb.
Now that's an epic solo. So is Time.
I'd have to say...*thinks for 10 minutes* Gee... *opens iTunes* Hmm... Maybe Jimi Hendrix's Star Spangled Banner / Purple Haze / solo at Woodstock. Or Dazed and Confused, Song Remains the Same soundtrack live, by Led Zeppelin. Or Sweet Child of Mine by Guns N' Roses.
I love the solos in Comfortably Numb. I also like the solo in Fade to Black by Metallica because it's really clean and fun to listen to. Hey Joe is fun to listen to as well.
No More Tears[b]. It's so hard to choose. I wanted to say November Rain, but it's not "a" solo, so have to go with Zak Wylde's work. Eruption by Van Halen, that's a good one. Um, Hot For Teacher is great as well. And there's always While My Guitar Gently Weeps[b].