in call of duty world at war when those japanese guys had grenades strapped to their chests and ran over to the general guy or whatever of my batallion and blew him up i guess was pretty sad. Also, not a video game, but in clear vision 2, whenu do that mission that u aren't allowed to pass and u have to free those hostages and u can only save one of them, or when u have to shoot the dog, it reminds me of the scene from i am legend that just broke my heart.